EB06690-T Goat Anti-APOE Antibody - Trial Size
Price: $100.00 / €100,00 / £75.00
Size: 20µg specific antibody in 40µl
EU Availability: In stock
US Availability: In stock
Click to add to EURO Shopping Cart (EU customers only)
Click to add to US Dollar Shopping Cart (US customers only)
Cart for UK (GBP) customers coming soon, meanwhile click for ordering info
EB06690 Goat Anti-APOE Antibody
Price: $285.00 / €292,50 / £195.00
Size: 100µg specific antibody in 200µl
EU Availability: In stock
US Availability: In stock
Click to add to EURO Shopping Cart (EU customers only)
Click to add to US Dollar Shopping Cart (US customers only)
Cart for UK (GBP) customers coming soon, meanwhile click for ordering info
Ordering Information As well as the shopping cart links above, you can order by email, phone, fax and mail. For country specific ordering information and shopping cart instructions please see Ordering Info. Please get in touch for world-beating prices on bulk orders and custom formulations. To order the immunizing peptide for blocking experiments please see Peptide Info.Target ProteinPrincipal Names: APOE; AD2; MGC1571; apoprotein; apolipoprotein E; apolipoprotein E3; Alzheimer disease 2 (APOE*E4-associated, late onset)
Official Symbol: APOE
Accession Number(s): NP_000032.1
Human GeneID(s): 348
Gene Ontology Terms: antioxidant activity; apolipoprotein E receptor binding; beta-amyloid binding; cholesterol homeostasis; circulation; cytoplasm; cytoskeleton organization and biogenesis; extracellular region; extracellular region; heparin binding; induction of apoptosis; intracellular transport; learning and/or memory; lipid binding; lipid transport; lipid transporter activity; lipoprotein metabolism; regulation of axon extension; regulation of neuronal synaptic plasticity; response to reactive oxygen species; synaptic transmission, cholinergic; tau protein binding
Immunogen Peptide with sequence C-VGTSAAPVPSDNH, from the C Terminus of the protein sequence according to NP_000032.1. Purification + Storage Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Aliquot and store at -20°C. Minimize freezing and thawing.Applications TestedPeptide ELISA: antibody detection limit dilution 1:32,000. Western Blot: Approx. 36kDa band observed in Human Brain lysates (calculated MW of 36.2kDa according to NP_000032.1). Recommended concentration: 0.1-0.3µg/ml.
Immunohistochemistry: In paraffin embedded Human Liver shows extra-cellular staining between hepatocytes. Recommended concentration, 2-4µg/ml.Species ReactivityTested: Human
Expected from sequence similarity: Human, Chimpanzee
Background ReferenceDodart JC, Marr RA, Koistinaho M, Gregersen BM, Malkani S, Verma IM, Paul SM.
Gene delivery of human apolipoprotein E alters brain A{beta} burden in a mouse model of Alzheimer's disease.
Proc Natl Acad Sci U S A. 2005 Jan 25;102(4):1211-6. Epub 2005 Jan 18.
PMID: 15657137
Adobe PDF Version of Datasheet
For Research purposes only. Not for diagnostic or in vivo use.
© Copyright Everest Biotech Ltd 2009 | Elite Grade Product 
EB06690 (0.1µg/ml) staining of Human Brain lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
EB06690 (2.5µg/ml) staining of paraffin embedded Human Liver. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. |
