EB06651 Goat Anti-Integrin beta 5 Antibody
Price: $185.00 / €187,50 / £125.00
Size: 100µg specific antibody in 200µl
EU Availability: In stock
US Availability: In stock
Click to add to EURO Shopping Cart (EU customers only)
Click to add to US Dollar Shopping Cart (US customers only)
Cart for UK (GBP) customers coming soon, meanwhile click for ordering info
Ordering Information As well as the shopping cart links above, you can order by email, phone, fax and mail. For country specific ordering information and shopping cart instructions please see Ordering Info. Please get in touch for world-beating prices on bulk orders and custom formulations. To order the immunizing peptide for blocking experiments please see Peptide Info.Target ProteinPrincipal Names: ITGB5; integrin, beta 5
Official Symbol: ITGB5
Accession Number(s): NP_002204.2
Human GeneID(s): 3693
Non-Human GeneID(s): 16419 (mouse);
Gene Ontology Terms: cell-matrix adhesion; development; integral to membrane; integrin complex; integrin-mediated signaling pathway; protein binding; receptor activity
Immunogen Peptide with sequence C-TFNKFNKSYNGTVD, from the C Terminus of the protein sequence according to NP_002204.2. Purification + Storage Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Aliquot and store at -20°C. Minimize freezing and thawing.Applications TestedPeptide ELISA: antibody detection limit dilution 1:16,000. Western Blot: Approx 110kDa band observed in Human Ovary and Mouse Eye lysates (calculated MW of 88.1kDa according to NP_002204.2). Recommended concentration: 0.1-0.3µg/ml.
Customer feedback: observed 110kDa in Mouse Eye was confirmed and not present in knock-out mouse.
Species ReactivityTested: Human
Expected from sequence similarity: Human, Mouse
Background ReferenceFinnemann SC, Bonilha VL, Marmorstein AD, Rodriguez-Boulan E.
Phagocytosis of rod outer segments by retinal pigment epithelial cells requires alpha(v)beta5 integrin for binding but not for internalization.
Proc Natl Acad Sci U S A. 1997 Nov 25;94(24):12932-7.
PMID: 9371778
Adobe PDF Version of Datasheet
For Research purposes only. Not for diagnostic or in vivo use.
© Copyright Everest Biotech Ltd 2009 | Aspiring Grade Product 
Please note, this product is one of a range of Aspiring Grade antibodies, made against targets that have limited or no commercial antibodies available to them and for which there are no data on the expression of the protein in the range of common cell lines and tissues available to us. These antibodies are affinity purified using their peptide immunogen and are known to give low background staining in a western blot (see Application Notes below). However no additional claims are made for their ability to recognise native protein in any application. |
