EB06387 Goat Anti-3'hExo / THEX1 Antibody
Price: $185.00 / €187,50 / £125.00
Size: 100µg specific antibody in 200µl
EU Availability: Currently out of stock - Please email sales@everestbiotech.com for delivery estimate
US Availability: In stock
Click to add to EURO Shopping Cart (EU customers only)
Click to add to US Dollar Shopping Cart (US customers only)
Cart for UK (GBP) customers coming soon, meanwhile click for ordering info
Ordering Information As well as the shopping cart links above, you can order by email, phone, fax and mail. For country specific ordering information and shopping cart instructions please see Ordering Info. Please get in touch for world-beating prices on bulk orders and custom formulations. To order the immunizing peptide for blocking experiments please see Peptide Info.Target ProteinPrincipal Names: 3'HEXO; MGC35395; 3' exoribonuclease; 3'-5' exonuclease ERI1; THEX1; three prime histone mRNA exonuclease 1
Official Symbol: THEX1
Accession Number(s): NP_699163
Human GeneID(s): 90459
Gene Ontology Terms: exonuclease activity; DNA binding; nucleus
Immunogen Peptide with sequence EDPQSKEPAGEA-C, from the N Terminus of the protein sequence according to NP_699163. Purification + Storage Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Aliquot and store at -20°C. Minimize freezing and thawing.Applications TestedPeptide ELISA: antibody detection limit dilution 1:4,000. Western Blot: Preliminary experiments gave no signal but low background in Human Brain and Liver lysates at up to 1µg/ml. We would appreciate any feedback from people in the field - have any results been reported with other antibodies/lysates?
Species ReactivityTested:
Expected from sequence similarity: Human
Background ReferenceDominski Z, Yang XC, Kaygun H, Dadlez M, Marzluff WF.
A 3' exonuclease that specifically interacts with the 3' end of histone mRNA.
Mol Cell. 2003 Aug;12(2):295-305.
PMID: 14536070
Adobe PDF Version of Datasheet
For Research purposes only. Not for diagnostic or in vivo use.
© Copyright Everest Biotech Ltd 2009 | Aspiring Grade Product 
Please note, this product is one of a range of Aspiring Grade antibodies, made against targets that have limited or no commercial antibodies available to them and for which there are no data on the expression of the protein in the range of common cell lines and tissues available to us. These antibodies are affinity purified using their peptide immunogen and are known to give low background staining in a western blot (see Application Notes below). However no additional claims are made for their ability to recognise native protein in any application. |
