EB06383 Goat Anti-Munc13-4 / UNC13D (C terminus) Antibody
Price: $285.00 / €292,50 / £195.00
Size: 100µg specific antibody in 200µl
EU Availability: In stock
US Availability: In stock
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Ordering Information As well as the shopping cart links above, you can order by email, phone, fax and mail. For country specific ordering information and shopping cart instructions please see Ordering Info. Please get in touch for world-beating prices on bulk orders and custom formulations. To order the immunizing peptide for blocking experiments please see Peptide Info.Target ProteinPrincipal Names: UNC13D; unc-13 homolog D (C. elegans) ; FHL3; HLH3; HPLH3; Munc13-4 ; unc-13 homolog D
Official Symbol: UNC13D
Accession Number(s): NP_954712.1
Human GeneID(s): 201294
Immunogen Peptide with sequence C-KQASQHALRPAP, from the C Terminus of the protein sequence according to NP_954712.1. Purification + Storage Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Aliquot and store at -20°C. Minimize freezing and thawing.Applications TestedPeptide ELISA: antibody detection limit dilution 1:16,000. Western Blot: Approx. 105kDa band observed in Human T-lymphocyte and HeLa lysates (calculated MW of 123kDa according to NP_954712.1). Recommended concentration: 1-3µg/ml.
Full caption: EB06383 (2µg/ml) staining of Human T-lymphocyte lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Data provided by anonymous customer.Species ReactivityTested: Human
Expected from sequence similarity: Human
Background ReferenceFeldmann J, Callebaut I, Raposo G, Certain S, Bacq D, Dumont C, Lambert N, Ouachee-Chardin M, Chedeville G, Tamary H, Minard-Colin V, Vilmer E, Blanche S, Le Deist F, Fischer A, de Saint Basile G.
Munc13-4 is essential for cytolytic granules fusion and is mutated in a form of familial hemophagocytic lymphohistiocytosis (FHL3).
Cell. 2003 Nov 14;115(4):461-73.
PMID: 14622600
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For Research purposes only. Not for diagnostic or in vivo use.
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EB06383 (2µg/ml) staining of Human T-lymphocyte lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. |
