EB05934 Goat Anti-MERTK Antibody
Price: $185.00 / €187,50 / £125.00
Size: 100µg specific antibody in 200µl
EU Availability: In stock
US Availability: In stock
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Ordering Information As well as the shopping cart links above, you can order by email, phone, fax and mail. For country specific ordering information and shopping cart instructions please see Ordering Info. Please get in touch for world-beating prices on bulk orders and custom formulations. To order the immunizing peptide for blocking experiments please see Peptide Info.Target ProteinPrincipal Names: MERTK; c-mer proto-oncogene tyrosine kinase; mer; C-MER; c-mer
Official Symbol: MERTK
Accession Number(s): NP_006334
Human GeneID(s): 10461
Gene Ontology Terms: transmembrane receptor protein tyrosine kinase activity; ATP binding; receptor activity; cell growth and/or maintenance; vision; protein amino acid phosphorylation; cell surface receptor linked signal transduction; cell-cell signaling; soluble fraction; integral to plasma membrane; transferase activity
Immunogen Peptide with sequence C-DSSEGSEVLM, from the C Terminus of the protein sequence according to NP_006334. Purification + Storage Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Aliquot and store at -20°C. Minimize freezing and thawing.Applications TestedPeptide ELISA: antibody detection limit dilution 1:2000. Western Blot: Approx. 30kDa band observed in Human Brain, Human Ovary, Human Kidney, MOLT-4 and U937 lysates at 1ug of primary. Please note that the band we observe is different from the predicted size of approx. 115kDa according to NP_006334. Currently we cannot find an explanation for this in the literature. We would appreciate any feedback from people in the field - have any results been reported with other antibodies/lysates? Have any splice variants/modified forms been reported?
Species ReactivityTested:
Expected from sequence similarity: Human
Background ReferenceGraham DK, Dawson TL, Mullaney DL, Snodgrass HR, Earp HS.
Cloning and mRNA expression analysis of a novel human protooncogene, c-mer.
Cell Growth Differ. 1994 Jun;5(6):647-57.
PMID: 8086340
Adobe PDF Version of Datasheet
For Research purposes only. Not for diagnostic or in vivo use.
© Copyright Everest Biotech Ltd 2009 | Aspiring Grade Product 
Please note, this product is one of a range of Aspiring Grade antibodies, made against targets that have limited or no commercial antibodies available to them and for which there are no data on the expression of the protein in the range of common cell lines and tissues available to us. These antibodies are affinity purified using their peptide immunogen and are known to give low background staining in a western blot (see Application Notes below). However no additional claims are made for their ability to recognise native protein in any application. |
