EB05671 Goat Anti-CYLN2 Antibody
Price: $185.00 / €187,50 / £125.00
Size: 100µg specific antibody in 200µl
EU Availability: In stock
US Availability: In stock
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Ordering Information As well as the shopping cart links above, you can order by email, phone, fax and mail. For country specific ordering information and shopping cart instructions please see Ordering Info. Please get in touch for world-beating prices on bulk orders and custom formulations. To order the immunizing peptide for blocking experiments please see Peptide Info.Target ProteinPrincipal Names: CYLN2; cytoplasmic linker 2; WSCR4; WBSCR4; CLIP-115; KIAA0291; MGC11333; Williams-Beuren syndrome chromosome region 4
Official Symbol: CYLN2
Accession Number(s): NP_003379; NP_115797
Human GeneID(s): 7461
Gene Ontology Terms: microtubule associated protein
Important Comments: This antibody is expected to recognise both human isoforms of this protein, as represented by NP_003379 and NP_115797. Immunogen Peptide with sequence C-HQQDKAQKQEDKH, from the C Terminus of the protein sequence according to NP_003379; NP_115797. Purification + Storage Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Aliquot and store at -20°C. Minimize freezing and thawing.Applications TestedPeptide ELISA: antibody detection limit dilution >1:32,000. Western Blot: Preliminary experiments gave 3 bands at approx 150kDa, 125kDa and 100kDa in human brain lysates at 0.1ug/ml. Please note that currently we cannot find an explanation in the literature for the bands we observe given the predicted size of approx. 120kDda and 116kDa according to NP_003379 and NP_115797. We would appreciate any feedback from people in the field - have any results been reported with other antibodies/lysates? Have any further splice variants/modified forms been reported?
Species ReactivityTested:
Expected from sequence similarity: Human
Background ReferenceOsborne LR, Martindale D, Scherer SW, Shi XM, Huizenga J, Heng HH, Costa T, Pober B, Lew L, Brinkman J, Rommens J, Koop B, Tsui LC.
Identification of genes from a 500-kb region at 7q11.23 that is commonly deleted in Williams syndrome patients.
Genomics. 1996 Sep 1;36(2):328-36.
PMID: 8812460
Adobe PDF Version of Datasheet
For Research purposes only. Not for diagnostic or in vivo use.
© Copyright Everest Biotech Ltd 2009 | Aspiring Grade Product 
Please note, this product is one of a range of Aspiring Grade antibodies, made against targets that have limited or no commercial antibodies available to them and for which there are no data on the expression of the protein in the range of common cell lines and tissues available to us. These antibodies are affinity purified using their peptide immunogen and are known to give low background staining in a western blot (see Application Notes below). However no additional claims are made for their ability to recognise native protein in any application. |
