EB05382-T Goat Anti-ADAM17 / TACE Antibody - Trial Size
Price: $100.00 / €100,00 / £75.00
Size: 20µg specific antibody in 40µl
EU Availability: In stock
US Availability: In stock
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EB05382 Goat Anti-ADAM17 / TACE Antibody
Price: $285.00 / €292,50 / £195.00
Size: 100µg specific antibody in 200µl
EU Availability: In stock
US Availability: In stock
Click to add to EURO Shopping Cart (EU customers only)
Click to add to US Dollar Shopping Cart (US customers only)
Cart for UK (GBP) customers coming soon, meanwhile click for ordering info
Ordering Information As well as the shopping cart links above, you can order by email, phone, fax and mail. For country specific ordering information and shopping cart instructions please see Ordering Info. Please get in touch for world-beating prices on bulk orders and custom formulations. To order the immunizing peptide for blocking experiments please see Peptide Info.Target ProteinPrincipal Names: ADAM17; TACE; a disintegrin and metalloproteinase domain 17 (tumor necrosis factor, alpha, converting enzyme); CSVP; cSVP; CD156b; CD156b; MGC71942; TACE; cSVPADAM metallopeptidase domain 17; TNF-alpha converting enzyme; a disintegrin and metalloproteinase domain 17; a disintegrin and metalloproteinase domain 17 (tumor necrosis factor, alpha, converting enzyme); snake venom-like protease
Official Symbol: ADAM17
Accession Number(s): NP_003174.3
Human GeneID(s): 6868
Non-Human GeneID(s): 11491 (mouse);
Gene Ontology Terms: metallopeptidase; cell-cell signalling; integral plasma membrane protein; peripheral plasma membrane protein
Important Comments: This antibody is expected to recognise isoform 1 (represented by NP_003174) and not isoform 2 (represented by NP_068604). Immunogen Peptide with sequence LQRQNRVDSKETEC, from the C Terminus of the protein sequence according to NP_003174.3. Purification + Storage Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Aliquot and store at -20°C. Minimize freezing and thawing.Applications TestedPeptide ELISA: antibody detection limit dilution 1:128,000. Western Blot: Approx 100kDa band observed in human testis lysates (calculated MW of 93.0kDa according to NP_003174.3). Recommended concentration: 0.1-0.3µg/ml.
Species ReactivityTested: Human
Expected from sequence similarity: Human, Mouse, Rat, Chinese Hamster
Background ReferenceBlack RA, Rauch CT, Kozlosky CJ, Peschon JJ, Slack JL, Wolfson MF, Castner BJ, Stocking KL, Reddy P, Srinivasan S, Nelson N, Boiani N, Schooley KA, Gerhart M, Davis R, Fitzner JN, Johnson RS, Paxton RJ, March CJ, Cerretti DP
A metalloproteinase disintegrin that releases tumour-necrosis factor-alpha from cells.
Nature. 1997 Feb 20;385(6618):729-33
PMID: 9034190
Adobe PDF Version of Datasheet
For Research purposes only. Not for diagnostic or in vivo use.
© Copyright Everest Biotech Ltd 2009 | Elite Grade Product 
EB05382 staining (0.2µg/ml) of Hela lysate (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. |
