EB05318 Goat Anti-DUSP8 / HVH5 Antibody Price: $285.00 / €292,50 / £195.00 Size: 100µg specific antibody in 200µl EU Availability: In stock US Availability: In stock Click to add to EURO Shopping Cart (EU customers only) Click to add to US Dollar Shopping Cart (US customers only) Cart for UK (GBP) customers coming soon, meanwhile click for ordering info
Ordering Information As well as the shopping cart links above, you can order by email, phone, fax and mail. For country specific ordering information and shopping cart instructions please see Ordering Info. Please get in touch for world-beating prices on bulk orders and custom formulations. To order the immunizing peptide for blocking experiments please see Peptide Info.Target ProteinPrincipal Names: DUSP8; dual specificity phosphatase 8; HB5; HVH8; HVH-5; H1 phosphatase, vaccinia virus homolog; serine/threonine specific protein phosphatase Official Symbol: DUSP8 Accession Number(s): NP_004411.1 Human GeneID(s): 1850 Non-Human GeneID(s): 18218 (mouse); Gene Ontology Terms: protein phosphatase type 2C activity; protein phosphatase type 2A activity; protein tyrosine phosphatase activity; inactivation of MAPK; protein amino acid dephosphorylation; cytoplasm; nucleus; calcium-dependent protein serine/threonine phosphatase activity; magnesium-dependent protein serine/threonine phosphatase activity; CTD phosphatase activity; hydrolase activity; MAP kinase phosphatase activity; myosin phosphatase activity; protein phosphatase type 2B activity Important Comments: This antibody is also expected to recognise the hypothetical human protein similar to dual specificity phosphatase 8 (XM_114902), which is virtually identical. Immunogen Peptide with sequence *AGDRLPRKVMDAK-C, from the N Terminus of the protein sequence according to NP_004411.1. Purification + Storage Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.Applications TestedWestern blot: Approx 60-65kDa bands seen in Human Heart lysate. Recommended for use at 1-3µg/ml.
Species ReactivityTested: Human Expected from sequence similarity: Human, Mouse Background ReferenceMartell KJ, Seasholtz AF, Kwak SP, Clemens KK, Dixon JE. hVH-5: a protein tyrosine phosphatase abundant in brain that inactivates mitogen-activated protein kinase. J Neurochem. 1995 Oct;65(4):1823-33. PMID: 7561881
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For Research purposes only. Not for diagnostic or in vivo use. © Copyright Everest Biotech Ltd 2009 | Elite Grade Product 

EB05318 staining (2µg/ml) of Human Heart lysate (RIPA buffer, 30µg total protein per lane). Primary incubated for 12 hour. Detected by western blot using chemiluminescence. |